2006 Mercedes-Benz E350 Transmission & Power Train Problems
NHTSA component category: POWER TRAIN · data through 07/14/2026
Source: U.S. NHTSA complaint data. Complaints are unverified reports from vehicle owners — a complaint is not a confirmed defect.
How power train ranks on this vehicle
Share of the 398 complaints citing each category; one complaint can cite several. Full breakdown on the 2006 Mercedes-Benz E350 overview page.
What owners report
“I WAS DRIVING ON THE HIGHWAY AND COULD HEAR THAT THE ENGINE DIDN'T SOUND RIGHT, IT WAS REVVING AT A HIGHER RPM THAN NORMAL. I…”NHTSA complaint 10480738 — filed 10/16/2012
“CAR HAS CHECK ENGINE LIGHT COME ON, DIAGNOSED TO HAVE BALANCE SHAFT FAILURE. THIS IS A WELL KNOWN DEFECT THAT HAPPENS TO MANY CARS WITH…”NHTSA complaint 10476514 — filed 09/20/2012
“BALANCE SHAFT FAILURE. AT 57,700 MILES THE CHECK ENGINE LIGHT ON WITH CODES 1200/1207 ALSO KNOWN AS P0016 AND P0017. THE BALANCE SHAFT SPROCKET IS…”NHTSA complaint 10453116 — filed 03/26/2012
Excerpts are shortened and scrubbed of personal details; they are individual, unverified reports.
Power Train complaints by year filed
Frequently asked questions
Does the 2006 Mercedes-Benz E350 have transmission & power train problems?
Power Train is the #5 most-reported problem area on the 2006 Mercedes-Benz E350: 29 of 398 complaints on file (7.3%). Complaints are unverified owner reports, not confirmed defects.
How many complaints does the 2006 Mercedes-Benz E350 have in total?
398 complaints were on file with NHTSA as of 07/14/2026. Across all categories, 14 involved a crash, 9 involved a fire, 18 reported injuries, and 1 reported deaths.
What does NHTSA's power train category include?
NHTSA groups complaints about the transmission (automatic or manual), driveline, axles, transfer case and related parts under a single component category called POWER TRAIN. This page reports that category as NHTSA defines it.
